Evaluation of the clinical performance of the cobas® 4800 1 HPV test in a colposcopy referred population

Title: Evaluation of the clinical performance of the cobas® 4800 1 HPV test in a colposcopy referred population
Authors: White, Christine
Keegan, Helen
Pilkington, Loretto
Ruttle, Carmel
Kerr, Patrick
Turner, Michael
Prendiville, Walter
D'Arcy, Tom
O'Leary, John J.
Martin, Cara M.
et al.
Permanent link: http://hdl.handle.net/10197/9202
Date: Oct-2013
Abstract: The clinical performance of the cobas human papillomavirus (HPV) test for detection of high-grade disease in a colposcopy-referred population was compared with that of Hybrid Capture 2 (HC2). The overall agreement between the tests was 92.3%. Clinical sensitivity and specificity for detection of cervical intraepithelial neoplasia grade 2 or greater (CIN2+) were 90.0% and 55.5% for cobas and 90.5% and 50.2% for HC2, respectively. In conclusion, both tests showed comparable performance for detection of CIN2+.
Funding Details: Health Research Board
Type of material: Journal Article
Publisher: American Society for Microbiology
Journal: European Journal of Clinical Microbiology
Volume: 51
Issue: 10
Start page: 3415
End page: 3417
Copyright (published version): 2013 American Society for Microbiology
Keywords: Virology
DOI: 10.1128/JCM.01949-13
Language: en
Status of Item: Peer reviewed
Appears in Collections:Medicine Research Collection

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