Cysteine, Glutathione and Thiol Redox Balance in Astrocytes

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Title: Cysteine, Glutathione and Thiol Redox Balance in Astrocytes
Authors: McBean, Gethin J.
Permanent link: http://hdl.handle.net/10197/9321
Date: 3-Aug-2017
Abstract: This review discusses the current understanding of cysteine and glutathione redox balance in astrocytes. Particular emphasis is placed on the impact of oxidative stress and astrocyte activation on pathways that provide cysteine as a precursor for glutathione. The effect of the disruption of thiol-containing amino acid metabolism on the antioxidant capacity of astrocytes is also discussed.
Type of material: Journal Article
Publisher: MDPI (Multidisciplinary Digital Publishing Institute)
Keywords: Cysteine;Cystine;Cysteamine;Cystathionine;Glutahione;xc− cystine-glutamate exchanger;Transsulfuration
DOI: 10.3390/antiox6030062
Language: en
Status of Item: Peer reviewed
Appears in Collections:Conway Institute Research Collection
Biomolecular and Biomedical Science Research Collection

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