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Cysteine, Glutathione and Thiol Redox Balance in Astrocytes
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| Download | McBean,_Cysteine,_glutathione_and_thiol_redox_balance_in_astrocytes_PRE-PUBLICATION.docx | 522.01 kB | Microsoft Word |
| Title: | Cysteine, Glutathione and Thiol Redox Balance in Astrocytes | Authors: | McBean, Gethin J. | Permanent link: | http://hdl.handle.net/10197/9321 | Date: | 3-Aug-2017 | Online since: | 2018-04-12T12:19:25Z | Abstract: | This review discusses the current understanding of cysteine and glutathione redox balance in astrocytes. Particular emphasis is placed on the impact of oxidative stress and astrocyte activation on pathways that provide cysteine as a precursor for glutathione. The effect of the disruption of thiol-containing amino acid metabolism on the antioxidant capacity of astrocytes is also discussed. | Funding Details: | Cystinosis Ireland | Type of material: | Journal Article | Publisher: | MDPI (Multidisciplinary Digital Publishing Institute) | Journal: | Antioxidants | Volume: | 6 | Issue: | 3 | Start page: | 62 | Keywords: | Cysteine; Cystine; Cysteamine; Cystathionine; Glutahione; xc− cystine-glutamate exchanger; Transsulfuration | DOI: | 10.3390/antiox6030062 | Language: | en | Status of Item: | Peer reviewed | This item is made available under a Creative Commons License: | https://creativecommons.org/licenses/by-nc-nd/3.0/ie/ |
| Appears in Collections: | Conway Institute Research Collection Biomolecular and Biomedical Science Research Collection |
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