Cysteine, Glutathione and Thiol Redox Balance in Astrocytes

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Title: Cysteine, Glutathione and Thiol Redox Balance in Astrocytes
Authors: McBean, Gethin J.
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Date: 3-Aug-2017
Online since: 2018-04-12T12:19:25Z
Abstract: This review discusses the current understanding of cysteine and glutathione redox balance in astrocytes. Particular emphasis is placed on the impact of oxidative stress and astrocyte activation on pathways that provide cysteine as a precursor for glutathione. The effect of the disruption of thiol-containing amino acid metabolism on the antioxidant capacity of astrocytes is also discussed.
Funding Details: Cystinosis Ireland
Type of material: Journal Article
Publisher: MDPI (Multidisciplinary Digital Publishing Institute)
Journal: Antioxidants
Volume: 6
Issue: 3
Start page: 62
Keywords: CysteineCystineCysteamineCystathionineGlutahionexc− cystine-glutamate exchangerTranssulfuration
DOI: 10.3390/antiox6030062
Language: en
Status of Item: Peer reviewed
This item is made available under a Creative Commons License:
Appears in Collections:Conway Institute Research Collection
Biomolecular and Biomedical Science Research Collection

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