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Metabolomics Based Dietary Biomarkers in Nutritional Epidemiologyâ Current Status and Future Opportunities
Author(s)
Date Issued
2018-04-24
Date Available
2019-04-16T10:05:41Z
Abstract
The application of metabolomics in nutrition epidemiology holds great promise and there is a high expectation that it will play a leading role in deciphering the interactions between diet and health. However, while significant progress has been made in identification of putative biomarkers more work is needed to address the use of the biomarkers in dietary assessment. The aim of this review to critically evaluate progress in these areas and to identify challenges that need to be addressed going forward. The notable applications of dietary biomarkers in nutritional epidemiology include (1) Determination of food intake based on biomarkers levels and calibration equations from feeding studies (2) Classification of individuals into dietary patterns based on the urinary metabolic profile and (3) Application of metabolome-wide-association studies. Further work is needed to address some specific challenges to enable biomarkers to reach their full potential.
Sponsorship
European Research Council
Science Foundation Ireland
Type of Material
Journal Article
Publisher
Wiley
Journal
Molecular Nutrition and Food Research
Volume
63
Issue
1
Copyright (Published Version)
2018 WILEYâVCH Verlag GmbH & Co. KGaA, Weinheim
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
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