Metabolomics Based Dietary Biomarkers in Nutritional Epidemiology‐ Current Status and Future Opportunities

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Title: Metabolomics Based Dietary Biomarkers in Nutritional Epidemiology‐ Current Status and Future Opportunities
Authors: Brennan, Lorraine
Hu, Frank B.
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Date: 24-Apr-2018
Online since: 2019-04-16T10:05:41Z
Abstract: The application of metabolomics in nutrition epidemiology holds great promise and there is a high expectation that it will play a leading role in deciphering the interactions between diet and health. However, while significant progress has been made in identification of putative biomarkers more work is needed to address the use of the biomarkers in dietary assessment. The aim of this review to critically evaluate progress in these areas and to identify challenges that need to be addressed going forward. The notable applications of dietary biomarkers in nutritional epidemiology include (1) Determination of food intake based on biomarkers levels and calibration equations from feeding studies (2) Classification of individuals into dietary patterns based on the urinary metabolic profile and (3) Application of metabolome-wide-association studies. Further work is needed to address some specific challenges to enable biomarkers to reach their full potential.
Funding Details: European Research Council
Science Foundation Ireland
Type of material: Journal Article
Publisher: Wiley
Journal: Molecular Nutrition and Food Research
Volume: 63
Issue: 1
Copyright (published version): 2018 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim
Keywords: MetabolomicsDietary biomarkersFood intakeDietary assessment
DOI: 10.1002/mnfr.201701064
Language: en
Status of Item: Peer reviewed
Appears in Collections:Agriculture and Food Science Research Collection

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