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  5. Novel approach to the synthesis of aliphatic and aromatic alpha-keto acids
 
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Novel approach to the synthesis of aliphatic and aromatic alpha-keto acids

Author(s)
Balducci, Daniele  
Conway, Philip A.  
Sapuppo, Giulia  
Müller-Bunz, Helge  
Paradisi, Francesca  
Uri
http://hdl.handle.net/10197/3764
Date Issued
2012-09
Date Available
2012-08-24T15:44:19Z
Abstract
A new practical and efficient synthesis of alpha-keto acids was accomplished starting from the synthon 1,4-diacetylpiperazine-2,5-dione. The synthesis encompasses both aromatic and aliphatic substrates proving to be versatile and innovative with excellent carbon economy and recycling of the glycine by-product.
Sponsorship
Science Foundation Ireland
Higher Education Authority
Type of Material
Journal Article
Publisher
Elsevier
Journal
Tetrahedron
Volume
68
Issue
36
Start Page
7374
End Page
7379
Copyright (Published Version)
2012 Elsevier B.V
Subjects

Alpha-keto acids

Aliphatic

Aromatic

Aldol reaction

Subject – LCSH
Ketonic acids--Synthesis
Aliphatic compounds--Synthesis
Aromatic compounds--Synthesis
DOI
10.1016/j.tet.2012.06.078
Language
English
Status of Item
Peer reviewed
This item is made available under a Creative Commons License
https://creativecommons.org/licenses/by-nc-sa/1.0/
File(s)
No Thumbnail Available
Name

Balducci Tetrahedron 2012.doc

Size

1.77 MB

Format

Microsoft Word

Checksum (MD5)

6eae985166bb53db116fd2b9d7d71808

Owning collection
Chemistry Research Collection

Item descriptive metadata is released under a CC-0 (public domain) license: https://creativecommons.org/public-domain/cc0/.
All other content is subject to copyright.

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