García-Vaquero, MarcoMarcoGarcía-VaqueroMiranda, MartaMartaMirandaBenedito, José LuisJosé LuisBeneditoBlanco-Penedo, IsabelIsabelBlanco-PenedoLópez-Alonso, MartaMartaLópez-Alonso2020-03-062020-03-062011 Elsev2011-06Food and Chemical Toxicology0278-6915http://hdl.handle.net/10197/11302Considering that meat is an important source of metals exposure to humans it is important to explore trace element concentrations in different types of muscles. Because of the demonstrated effect of Cu-supplementation on mineral status, the influence of Cu-supplementation was also evaluated. Samples of four different muscles (diaphragm, cardiac, semitendinous and pectoral, n=120) from beef calves receiving typical commercial diets Cu-supplemented (15mg Cu2SO4/kg DM) and non-supplemented were taken and acid digested. The levels of non-essential (As, Cd, Hg, Pb and Sn) and essential (Co, Cr, Fe, Mn, Mo, Ni, Se and Zn) elements were analyzed by ICP-MS. The statistical analyzes included two way Anova, post hoc DHS Tukey and Spearman correlations. The most active and less fat containing muscles showed in general the highest essential and the lowest non-essential trace element accumulation. As and Hg muscular residues are indicative of animal exposure, however, in situations of an adequate mineral status, essential trace element concentrations in muscle are irrespective of the mineral status of the animal and could be possibly related to their own particular muscular metabolism. Cu-supplementation significantly reduced As but caused a significant decrease of Se, which could have significance for the animal's health.Print-ElectronicenThis is the author’s version of a work that was accepted for publication in Food and Chemical Toxicology. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Food and Chemical Toxicology (49, 6, (2011)) DOI: https://doi.org/10.1016/j.fct.2011.03.041Skeletal muscleDiaphragmMyocardiumAnimalsCattleSeleniumTrace elementsCopper sulfateFood contaminationDietary supplementsMeat productsJournal Article4961443144910.1016/j.fct.2011.03.0412020-02-2107MRU030261Phttps://creativecommons.org/licenses/by-nc-nd/3.0/ie/