Charmsaz, SaraSaraCharmsazPrencipe, MariaMariaPrencipeKiely, MaeveMaeveKielyet al.2019-07-022019-07-022018 the A2018-06-19Cancers2072-6694http://hdl.handle.net/10197/10835Conventional therapies for cancer such as chemotherapy and radiotherapy remain a mainstay in treatment, but in many cases a targeted approach is lacking, and patients can be vulnerable to drug resistance. In recent years, novel concepts have been emerging to improve the traditional therapeutic options in cancers with poor survival outcomes. New therapeutic strategies involving areas like energy metabolism and extracellular vesicles along with advances in immunotherapy and nanotechnology are driving the next generation of cancer treatments. The development of fields such as theranostics in nanomedicine is also opening new doors for targeted drug delivery and nano-imaging. Here we discuss the use of innovative technologies presented at the Irish Association for Cancer Research (IACR) Annual Meeting, highlighting examples of where new approaches may lead to promising new treatment options for a range of cancer types.ElectronicenThis is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).Cancer therapeuticsEmerging technologiesNanomedicineComputational imagingCellular stressRadiosensitizingExosomesJournal Article1061910.3390/cancers100602082019-06-28https://creativecommons.org/licenses/by-nc-nd/3.0/ie/