Alterations in Motor Unit Firing Rate and Action Potential Properties during Isometric Fatigue in Stroke Survivors

The limited number of studies that have investigated fatigue in chronic stroke survivors during voluntary contr actions to the endurance limit have reported relatively higher central fatigue and lower peripher al fatigue on the affected side when compared to the less-affected side and healthy controls (Riley and Bilodeau, 2002; Knorr et al., 2011). Although these changes have been investigated using global indices of motor unit (MU) activation, alterations at th e level of the single motor unit have not yet been examined.