Increased EMG intermuscular coherence and reduced signal complexity in Parkinson's disease

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Title: Increased EMG intermuscular coherence and reduced signal complexity in Parkinson's disease
Authors: Flood, Matthew W.
Jensen, Bente Rona
Malling, Anne-Sofie
Lowery, Madeleine M.
Permanent link: http://hdl.handle.net/10197/10668
Date: Feb-2019
Online since: 2019-05-27T10:21:53Z
Abstract: Objectives: To investigate differences in surface electromyography (EMG) features in individuals with idiopathic Parkinson's disease (PD) and aged-matched controls. Methods: Surface EMG was recorded during isometric leg extension in PD patients prior to, and after undergoing a locomotor training programme, and in aged-matched controls. Differences in EMG structure were quantified using determinism (%DET), sample entropy (SampEn) and intermuscular coherence. Results: %DET was significantly higher, and SampEn significantly lower, in PD patients. Intermuscular coherence was also significantly higher in the PD group in theta, alpha and beta frequency bands. %DET increased and SampEn decreased with increasing Movement-Disorder-Society UPDRS scores, while theta band coherence was significantly correlated with total MDS-UPDRS scores and torque variance. Neither %DET, SampEn nor intermuscular coherence changed in response to training. Conclusions: The differences observed are consistent with increased synchrony among motor units within and across leg muscles in PD. Differences between EMG signals recorded from the PD and control groups persisted post-therapy, after improvements in walking capacity occurred. Significance: These results provide insight into changes in motoneuron activity in PD, demonstrate increased beta band intramuscular coherence in PD for the first time, and support the development of quantitative biomarkers for PD based on advanced surface EMG features.
Funding Details: European Research Council
Science Foundation Ireland
Type of material: Journal Article
Publisher: Elsevier
Journal: Clinical Neurophysiology
Volume: 130
Issue: 2
Start page: 259
End page: 269
Copyright (published version): 2018 International Federation of Clinical Neurophysiology
Keywords: ElectromyographyCoherenceDeterminismEntropySynchronizationParkinson’s disease
DOI: 10.1016/j.clinph.2018.10.023
Language: en
Status of Item: Peer reviewed
Appears in Collections:Electrical and Electronic Engineering Research Collection
Insight Research Collection

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